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A picture of colorful buildings in Cartagena, Columbia on a Panama Canal cruise

Cartagena, Colombia

Its official name is Cartagena de Indias—or "Cartagena of the Indies"—but call it Cartagena for short. The formal name hints at this Colombian city's colonial relationship with Spain; it was founded in 1533 and named after the mother country's Cartagena. Colombia declared independence in 1810, but there's plenty about its fifth-largest city that evokes old Spain, including the impressive fort of Castillo San Felipe de Barajas, and the wall that encloses the old town, one of the few intact structures of its kind in the Americas. Both were considered important enough to inscribe on UNESCO's list of World Heritage Sites in 1984. They may be historical artifacts, but the fortress and wall aren't merely tourist attractions; they are central to daily life here. Take a stroll and you'll see couples sitting atop the wall, locked in passionate embraces; parents watching their children walk it like a balance beam; and friends chatting while enjoying the Caribbean breeze. Along with history, there's cultural and culinary intrigue here, too. This colorful city was a muse of the late Nobel Prize–winning writer Gabriel García Márquez, and is increasingly being recognized outside Colombia for its cuisine, which takes many cues from Caribbean ingredients. (Don't leave without trying the coconut rice.)

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