Cruises From San Diego, California

Before you cruise from San Diego, explore this laid-back surfer town that enjoys more than 300 days of sunshine, mild year-round temperatures and accessible outdoor activities. Hike the Torrey Pines State Natural Reserve to get a glimpse of whale migrations, go sailing in the bay and, of course, surf the famous swells of Del Mar, Oceanside and La Jolla. But the sixth-largest city in the United States also has some surprising neighborhoods: Old Town, North Park, Point Loma and Coronado are all within a few miles of the port, while the Gaslamp Quarter and Little Italy are also within walking distance. Watch the city skyline fade as you cruise from San Diego to Mexico’s ancient ruins or to the turquoise waters of Hawaii and Tahiti, or to the Panama Canal and Central America.
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Featured Itineraries Departing San Diego

See the World From Your Doorstep

From San Diego, coast turquoise waters to Hawaii, Tahiti and remote South Pacific Islands; cross between oceans at the Panama Canal; experience Mexico’s vibrant cultural heritage; or sweep the Pacific Coast’s beaches and vineyards. Visit 225 ports in 91 countries from the U.S. and Canada.

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Things To Do In San Diego

Find top picks of things to do before or after your cruise from San Diego.

BALBOA PARK

Visit the largest urban cultural park in the U.S. It houses 15 museums, performing-arts venues, incredible gardens and the world-famous San Diego Zoo. You can spend days seeing all of its attractions, including the United Nations Building, Spanish Village Art Center and Alcazar Garden.

GASLAMP QUARTER

The Gaslamp Quarter is a must on cruises out of San Diego. Explore Victorian architecture, shopping, dining and art galleries, only a pleasant two-mile stroll (or two-stop trolley ride) from the Port of San Diego. You could even check out a baseball game at Petco Park.

LA JOLLA VILLAGE

The affluent coastal village of La Jolla is known for its beautiful beaches and sophisticated dining and shopping. One of the best ways to see La Jolla is from the water, via kayak: Spot dolphins, enjoy views of the dramatic shoreline or take a tour of Sunny Jim Sea Cave.

More Information About Cruises from San Diego

Add to Your Cruise

Add flights, hotel packages and onboard celebrations to your cruise from San Diego.

Booking flights online with Flight Ease by Holland America Line.

Flight Ease

Holland America Line Flight Ease® offers specially negotiated low prices, a convenient and worry-free way to book air travel, late-arrival protection, and the freedom to change your flights with no change fees.

Overland Hotel

Pre/Post Cruise

Find exceptional City Stays & Pre/Post Overland Packages, which offer a seamless experience ashore to add to your cruise from San Diego.

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Celebrations On Board

Life should be celebrated! What better way than with a Holland America Line cruise? Let us create the perfect event while you relax and have the time of your life.

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Cruise Destination from San Diego

Cruises to Mexico

Cruise to Hawaii and Tahiti

Cruise along Pacific Coast and California

Cruise to Panama Canal