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Panama Canal Cruises
Move through a man-made marvel, watch for rare birds and other wildlife, and take in astonishing views.
Featured Panama Canal Cruises
Cross the world’s most famous shortcut off your bucket list your way. Choose either a full transit through the historic locks or a partial transit. Embark from Vancouver, Seattle, San Diego or Ft. Lauderdale.
Top Reasons to Cruise Panama Canal With Holland America
A Front-Row Seat to the Spectacular
Cruise through the jaw-dropping Panama Canal locks cocooned in comfort on a perfectly sized ship while your Cruise & Travel Director provides fascinating insights.
Sailings From East or West
Our 12- to 21-day Panama Canal cruises depart from Vancouver, Seattle, San Diego, and Ft. Lauderdale. Also new for 2025–2026 are our Panama Canal cruises sailing aboard Zuiderdam, which begin or end in Miami.
Diverse Ports of Call
Visit charming coastal towns in Mexico, El Salvador, and Costa Rica and taste the Caribbean’s vibrant flavors in Aruba and Cartagena.
Featured Panama Canal Cruise Ports
From Huatulco’s beautiful beaches and delectable Oaxacan cuisine to Cartagena’s colonial-era fortress and massive city walls, every day brings a new adventure on Panama Canal cruises.
Huatulco
- Try fresh Oaxacan dishes
- Tour archeological sites
With 9 bays and 36 beaches, you’re in for some serious natural beauty. Beyond the sand and surf, there is local cuisine to try, archeological sites to explore, and more than 225 avian species to set birders’ hearts aflutter.
Shore Excursions in the Panama Canal
Unique excursions await everyone on our Panama Canal cruises, from breezy aerial trams through the forest canopy to astounding wildlife encounters and guided city walks.
Authentic Emberá Native Village
Take a journey into the lives of the Emberá Native tribe, who maintain their traditions and lifestyle. Motor upriver at Chagres National Park to the Emberá village.
Authentic Emberá Native Village
Take a journey into the lives of the Emberá Native tribe, who maintain their traditions and lifestyle. Motor upriver at Chagres National Park to the Emberá village.
Panama Canal Cruise Articles
Things to do in Cartagena
Cartagena, or Cartagena de Indias (Cartagena of the Indies as it is officially known), is the jewel in Colombia’s cultural crown.
Puerto Caldera: Home Port
One of the stops along the Panama Canal route, Puerto Caldera is your gateway to the country’s mangroves and rainforests.
Visiting Panama Viejo
In Panama City, centuries-old buildings stand in the shadows of glass skyscrapers and luxury condos.
Explore Panama Canal with Holland America
Immerse yourself in unforgettable shore excursions, savor world-class dining, and enjoy exclusive entertainment on your Panama Canal cruise.Enjoy a Front-Row Seat to Panama Canal Wonders
Our mid-sized ships provide an intimate atmosphere, allowing you to experience the Panama Canal — one of the world's greatest engineering marvels. Enjoy extra space while lounging by the pool or taking in the breathtaking views from the deck or bow.
Need Help Planning? Contact Our Personal Cruise Consultants.
Our consultants answer your questions, arrange hotel stays and find the best fares. Try this free service today!