Skip to Main Content
A Holland America Cruise ship in the Panama Canal.

Panama Canal Cruises

Move through a man-made marvel, watch for rare birds and other wildlife, and take in astonishing views.

Top Reasons to Cruise Panama Canal With Holland America

A Front-Row Seat to the Spectacular

Cruise through the jaw-dropping Panama Canal locks cocooned in comfort on a perfectly sized ship while your Cruise & Travel Director provides fascinating insights.

Sailings From East or West

Our 12- to 21-day Panama Canal cruises depart from Vancouver, Seattle, San Diego, and Ft. Lauderdale.

Diverse Ports of Call

Visit charming coastal towns in Mexico, El Salvador, and Costa Rica and taste the Caribbean’s vibrant flavors in Aruba and Cartagena.

Sign Up for Special Offers

Be the first to know about exclusive cruise deals, new itineraries, and limited-time offers.

Sign Up

Featured Panama Canal Cruise Ports

From Huatulco’s beautiful beaches and delectable Oaxacan cuisine to Cartagena’s colonial-era fortress and massive city walls, every day brings a new adventure on Panama Canal cruises.

Huatulco

  • Try fresh Oaxacan dishes
  • Tour archeological sites

With 9 bays and 36 beaches, you’re in for some serious natural beauty. Beyond the sand and surf, there is local cuisine to try, archeological sites to explore, and more than 225 avian species to set birders’ hearts aflutter.

Explore Huatulco
Map showing the Huatulco, Mexico port.

Panama Canal Cruise Articles

Things to do in Cartagena Cartagena, or Cartagena de Indias (Cartagena of the Indies as it is officially known), is the jewel in Colombia’s cultural crown.
Puerto Caldera: Home Port One of the stops along the Panama Canal route, Puerto Caldera is your gateway to the country’s mangroves and rainforests.
Visiting Panama Viejo In Panama City, centuries-old buildings stand in the shadows of glass skyscrapers and luxury condos.
View Panama Canal Travel Tips

Panama Canal Cruise Articles

Things to do in Cartagena Cartagena, or Cartagena de Indias (Cartagena of the Indies as it is officially known), is the jewel in Colombia’s cultural crown.
Puerto Caldera: Home Port One of the stops along the Panama Canal route, Puerto Caldera is your gateway to the country’s mangroves and rainforests.
Visiting Panama Viejo In Panama City, centuries-old buildings stand in the shadows of glass skyscrapers and luxury condos.

Explore Panama Canal with Holland America

Immerse yourself in unforgettable shore excursions, savor world-class dining, and enjoy exclusive entertainment on your Panama Canal cruise.

Enjoy a Front-Row Seat to Panama Canal Wonders

Our mid-sized ships provide an intimate atmosphere, allowing you to experience the Panama Canal — one of the world's greatest engineering marvels. Enjoy extra space while lounging by the pool or taking in the breathtaking views from the deck or bow. 

 

Meet Our Ships

Cruise Travel Made Simple

From pre- and post-cruise flights and hotels to transportation, Holland America provides one-stop planning support for a seamless journey.

Book a Flight

The easiest way to book flights for your cruise.

Book a Hotel

Extend your trip with a pre- or post-cruise hotel stay.

Book Cruise Transportation

Travel to and from your cruise hassle-free.

Need Help Planning? Contact Our Personal Cruise Consultants.

Our consultants answer your questions, arrange hotel stays and find the best fares. Try this free service today!

Contact Us

Earn 20,000 Bonus Points

That's enough for a $200 onboard credit. Winner of The Trazees 2025 Favorite Cruise Line Credit Card!
Terms Apply.

 

We've made some updates to improve your experience.

Refresh the page to see the latest changes.