Visit Rome’s legendary Colosseum. Shop Monaco’s glamorous boutiques. Sample succulent tapas in Barcelona. Walk the medieval wall that guards Dubrovnik’s charms. Unwind under a canopy of stars. 


All of our cruise itineraries offer just the right balance of action-packed days in port with relaxing days at sea, plus extended hours and overnight stays in select cities. We also include more overnights at the beginning and end of our cruises, so you can spend an extra day exploring cities like Barcelona, Venice and Rome, and use the ship as your hotel. Whether you’re making your maiden voyage in the Mediterranean and want to see its more iconic sights or you’ve traveled here before and are hoping to experience some of its seldom-visited destinations, Holland America Line has the Mediterranean cruise vacation you’ve been waiting for.


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Mediterranean Cruise Ports & Regions

A Magical Night in Venice

Take a moonlit gondola ride through fabled waterways. Dine on freshly made pasta at a charming bistro. Enjoy a leisurely winery tour. Attend a classical concert in a Renaissance-era church and more—on an overnight in Venice.

Beautiful Barcelona

Las Ramblas, with its unrivalled people-watching; the curving, sinuous lines of Gaudí’s architectural masterpieces; the vibrant contemporary art scene and cuisine; make this Catalan capital a must-see for sophisticated travelers.

Charming Dubrovnik

Perched high above the Adriatic Sea, Dubrovnik is walled medieval city of cobblestone lanes and red terra cotta roofs, Explore St. Blaise Church, the Sponza Palace, the Rector’s Palace and other gems. Sip the region’s finest wines in Komaji.

italy's West Coast

A treasure trove of iconic sites, Italy’s west coast also has some remarkable hidden gems. AFAR deputy editor, Jenn Flowers, has recommendations for several seldom-seen “must see” places.

Ships serving Mediterranean Cruises


Our new flagship, and third Pinnacle-class ship, Rotterdam's premiere voyage sets sail August 2021. Discover Italy, Croatia and Greece on day trips filled with cultural intrigue.

Nieuw Statendam

Our new Pinnacle-class ship, Nieuw Statendam, made its debut in Europe in December 2018. Mediterranean cruises from 10 to 22 days set sail from Civitavecchia (Rome) or Amsterdam. Relax on a Santorini beach, enjoy tapas on Las Ramblas and more.


Westerdam sails roundtrip Mediterranean itineraries of 7 to 27 days, April through October. Explore ancient glories, Renaissance treasures and iconic European cities.


Volendam sails the Mediterranean May through October on cruises from 12 to 24 days. Soak up every drop of the region, including the wonders of Italy. Venture the Greek isles and the Adriatic coast for an immersive exploration.

Featured Shore Excursions

Mediterranean Cruise Itineraries

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12-Day Mediterranean Tapestry

Stroll the lavender fields of Provence. Explore the glories of Florence. Visit the ancient sites of Rome and Pompeii. Cruise the Strait of Messina.

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20-Day Best Of The Mediterranean

Dine on pizza in Naples, its birthplace. Revisit ancient Greece in Athens, Olympia and Ephesus. Visit the walled medieval Old Town of Dubrovnik. 

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10-Day Mediterranean Mosaic

Depart Rome for the marvels of Spain. With stops in Cartagena and Barcelona, you’ll uncover this region’s cultural wonders.

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